World Malaria Day : Understanding Malaria

Author: Turacoz Group
April 25, 2016

Malaria is a serious life-threatening parasitic disease caused by parasites known as Plasmodium vivax (P.vivax), Plasmodium falciparum (P.falciparum), Plasmodium malariae (P.malariae) and Plasmodium ovale (P.ovale). Its transmission takes place through the infective bite of Anopheles mosquito. Man develops this disease after 10–14 days of being bitten by an infective mosquito.

Every year April 25 is celebrated as “World Malaria Day” across the globe in an effort to provide effective control of the disease. This occasion also provides a common platform for the affected countries to share experiences, showcase technologies and collaborate in programs in the fight against malaria.

SIGNS AND SYMPTOMS OF MALARIA

Symptoms of malaria include fever and flu-like illness, including shaking chills, headache, muscle aches, and tiredness. Nausea, vomiting, and diarrhea may also occur. Malaria may cause anemia and jaundice (yellow coloring of the skin and eyes) because of the loss of red blood cells. Infection with one type of malaria, P. falciparum, if not promptly treated, may cause kidney failure, seizures, mental confusion, coma, and death.

POPULATION AT RISK

In 2015, approximately 3.2 billion people—nearly half of the world’s population—were at risk of malaria.

Maximum number of malaria cases and deaths occur in sub-Saharan Africa. However, Asia, Latin America, and, to a lesser degree, the Middle East, are also at risk. In 2015, 97 countries and territories had ongoing malaria transmission.

DISEASE BURDEN

  • According to the latest WHO estimates, released in December 2015, there were 214 million cases of malaria in 2015 and 438,000 deaths.
  • Between 2000 and 2015, malaria incidence among populations at risk reduced by 37% globally; during the same period, malaria mortality rates among populations at risk registered a decline by 60%. An estimated 6.2 million malaria deaths have been averted globally since 2001.
  • Sub-Saharan Africa continues to contributethe highest share of the global malaria burden. In 2015, the region accounted for 88% of malaria cases and 90% of malaria deaths.

PREVENTIVE MEASURES FOR CONTROLLING MALARIA

  • Taking antimalarial drugs to kill the parasites
  • Eliminating places where mosquitoes breed
  • Spraying insecticides to kill adult mosquitoes that come inside
  • Sleeping under bed nets—especially effective if they have been treated with insecticide, e.g. insecticide-treated mosquito nets (ITNs) and
  • Wearing insect repellent and long-sleeved clothing if out of doors at night.

CURRENT SCENARIO OF MALARIA VACCINE

  • Effective malaria vaccine could helpeliminate and eradicate malaria; there are currently 63 vaccine candidates, 41in preclinical and clinical stages of development.
  • Vaccines are being designedto target pre-erythrocytic stages, erythrocytic stage or the sexual stages ofPlasmodium taken up by a feeding mosquito, or the multiple stages
  • Twovaccines in preclinical and clinical development target falciparum; and themost advanced candidate is the pre-erythrocytic vaccine RTS,S which is inphase-III clinical trials.
  • RTS,S/ASO1 is the first malaria vaccine to have completed pivotal Phase 3 testing and obtained a positive scientific opinion by a stringent medicines regulatory authority.
  • Collaborators of RTS,S Clinical Trials Partnership showed that RTS,S/AS01 prevented a substantial number of cases of clinical malaria over a 3–4-year period in young infants and children when administered with or without a booster dose. Efficacy was enhanced by the administration of a booster dose in both age categories. Thus, the vaccine has the potential to make a substantial contribution to malaria control when used in combination with other effective control measures, especially in areas of high transmission.

Turacoz Healthcare Solutions is committed to spread the awareness on such social or healthcare related issues as a part of their Corporate Social Responsibility (CSR) activity. Our medical writing team is well versed with recent advances in various therapeutic areas which gives them a head start in various publication, clinical research and regulatory writing projects.

Tags: , , , , , ,

You Might Also Like

  • Top Benefits of Using Academic Research Writing Services

    “Write the paper as though no editor will ever see it … then let a good editor make sure everyone

  • World Thyroid Day 2025: How AI Is Revolutionizing Thyroid Health

    World Thyroid Day invites us to appreciate the tiny, butterfly-shaped gland with a big job in managing our body’s energy,

  • How AI is redefining content creation in pharma — And why humans are still the drivers of trust

    In an era where speed, efficiency, and personalization have become imperatives, Artificial Intelligence (AI) — particularly machine learning, AI algorithms,

  • World Thalassemia Day 2025: Giving a Voice to the Global Patient Community

    Every 8 May, World Thalassemia Day shines an international spotlight on the millions of people living with this inherited genetic disorder.

  • Decoding Ovarian Cancer Symptoms: Communicating the Silent Signs

    Ovarian cancer remains one of the most challenging gynaecologic malignancies, often referred to as a “silent killer” due to its subtle onset and late-stage diagnosis.1 In 2022, 324,603 women worldwide were diagnosed with ovarian cancer.

  • 4 Ways in Which HEOR is Transforming Healthcare with RWE

    The healthcare landscape is being reshaped at an unprecedented pace, powered by sophisticated data analytics, emerging technologies, and the escalating

  • The Role of HEOR in Payer Decisions to Switch from Originators to Biosimilars

    Biosimilars—biologic medicines that are highly similar to FDA-approved originator biologics—offer a cost-effective alternative without compromising clinical efficacy.1,2 Since the first

  • Content’s Industrial Revolution: Shaping the Future of Pharma

    Communications In a rapidly evolving digital ecosystem, the pharmaceutical industry’s relationship with content is undergoing a seismic shift. At the

  • Health Journalism: Combating Misinformation with Accuracy

    By Turacoz Healthcare Solutions | World Liver Day 2025 In a world where social media dominates wellness discussions, liver health

  • Patient Voices Matter: How Patient-reported Outcomes Are Redefining Market Access

    The healthcare industry is experiencing a paradigm shift as patient voices take center stage in drug development and approval processes.

Newsletter

Stay informed with the latest trends, insights, and updates in medical communications—download our newsletter now.

partner with us

Partner with Turacoz to bring science to life through strategic and evidence-based communication.

Partner with Us