When the balance of body’s metabolic processes is disrupted, certain conditions arise which are known as ‘metabolic conditions’, of which diabetes and obesity are at top of the list. These two metabolic conditions go hand in hand and are putting a major burden on global healtheconomy. The co-existence of these diseases is collectively known as ‘Diabesity’.According to WHO, the global burden of obesity has raised three times between the year 1975 and 2016, with more than 650 million obeseadults reported in 2016.The number of diabetics has grown from 108 million to 422 million from the year 1980 to 2014. WHO reports that around 50% of deaths in diabetic patients occur before the age of 70 years and it is predicted to be the seventh leading cause of mortalityby 2030. Hence, both diabetes and obesity are counted as the biggest concerns to human health and well-being.
Major reasons behind the raising epidemic status of diabesity include adoption of modern or sedentary lifestyle, fast food habits and relying on technology.Both diabetes and obesity come in a package with other health complications, reduced quality of life, and reduced life expectancy. The major associated challenges include myocardial infarction, cerebrovascular stroke, and renal diseases.
The pathophysiological mechanisms of diabetes and obesity are strongly inter-connected.Insulin resistance and beta cell dysfunction lead to diabetes. Body mass index, the direct measure of obesity, has been found to have positive association with insulin resistance, and consequently with diabetes. In obese people, non-esterified fatty acids, glycerol, hormones,cytokines, and proinflammatory markers are increased, which further lead to development of insulin resistance.Each kilogram rise in bodyweight has been reported to increase the risk of diabetes by 4.5%.
Various medical treatments that improve insulin sensitivity and beta cell functionare available to manage diabetes. Apart from pharmacological approaches, it is also important to practice lifestyle modifications, which not only impart benefits to the treatment, but also improvepatient’s quality of life. Consuminglow-calorie diet,doing regular exercise, maintaining weight, avoiding smoking and regular self-monitoring are highly beneficial in successfully improvement in health status of diabetics and obese patients.
We, at Turacoz Healthcare Solutions, believe that health is real wealth. In an attempt to reduce the global burden of diabetes and obesity, we wish to remind everyone to adopt healthy lifestyle.
“Write the paper as though no editor will ever see it … then let a good editor make sure everyone
World Thyroid Day invites us to appreciate the tiny, butterfly-shaped gland with a big job in managing our body’s energy,
In an era where speed, efficiency, and personalization have become imperatives, Artificial Intelligence (AI) — particularly machine learning, AI algorithms,
Every 8 May, World Thalassemia Day shines an international spotlight on the millions of people living with this inherited genetic disorder.
Ovarian cancer remains one of the most challenging gynaecologic malignancies, often referred to as a “silent killer” due to its subtle onset and late-stage diagnosis.1 In 2022, 324,603 women worldwide were diagnosed with ovarian cancer.
The healthcare landscape is being reshaped at an unprecedented pace, powered by sophisticated data analytics, emerging technologies, and the escalating
Biosimilars—biologic medicines that are highly similar to FDA-approved originator biologics—offer a cost-effective alternative without compromising clinical efficacy.1,2 Since the first
Communications In a rapidly evolving digital ecosystem, the pharmaceutical industry’s relationship with content is undergoing a seismic shift. At the
By Turacoz Healthcare Solutions | World Liver Day 2025 In a world where social media dominates wellness discussions, liver health
The healthcare industry is experiencing a paradigm shift as patient voices take center stage in drug development and approval processes.
Partner with Turacoz to bring science to life through strategic and evidence-based communication.