Tag Archives: #LiverCancer

#LiverCancerAwarenessMonth

Liver cancer: Treatment

Liver cancer treatment is generally based on the stage of disease and the patient response to treatment. Treatment is individualized as each patient respond differently. Based on the disease stage, the size, number, tumor location, other co-morbidities, overall health and well-being, the treatment is decided. Based on the complexity of the tumor a team of specialists are associated in the treatment. The team involves surgeons, oncologists, radiologists, gastroenterologists, radiation therapists, and pathologists.

Liver cancer is generally identified in patients who come to the hospitals with damaged livers. Also as the liver cancer stage increases the side effects also may become worse. Therefore, in order to be safe, best options to treat liver cancer should be chosen.

Treatment options

  • The best treatment option is to remove the liver surgically but only <10% of the patients are suitable for surgery. The reasons can be due to cirrhosis (due to bleeding, infection or liver failure), more tumors that are widespread to remove all. Even after successful surgery, there are some tiny deposits of tumors which are not even visible for the scans or surgery. The survival rate of patients having the surgery is >5 years.
  • Other option when there is no evidence of the spread of liver cancer includes liver transplantation. This method involves transplantation of a diseased liver with a healthy liver from a donor. Recent advances in transplantation techniques and immune medications have made transplantation the first choice for patients with cirrhosis and small tumors. The survival rate is >70% with >5 years.
  • Other possible options include injecting the liver with a toxic material such as pure alcohol or chemotherapy in order to destroy it, cryotherapy, radiofrequency ablation etc. These techniques are used in patients with only one or two small tumors, in general.
  • Chemoembolization which involves chemotherapy drugs which can be given directly into the blood vessel that feeds the liver and the tumors. This technique requires a hospital admission, and can cause pain, fever, nausea, and liver damage.
  • Radioembolization or selective internal radiation therapy (SIRT) which is almost similar to chemoembolization in which microscopic radioactive particles are used instead of chemotherapy injected into the blood vessels. This is as effective as chemoembolization for small and multiple tumors.
  • Radiation therapy which uses high-dose energy like X-rays aimed at a small part of the body and can frequently destroy cancer cells. In some cases other techniques like conformal or stereotactic radiation may be useful.

Liver cancer: outcomes

The best treatment options of all discussed above includes surgery and transplantation. Physicians with the help of several tests and scans determines the turmors. Although local treatments such as radiofrequency ablation, cryoablation, and chemoembolization can kill tumors that are visible, “new” tumors may develop which are invisible to the scan or tests. Also, the cirrhosis and conditions that gave rise to the initial cancers will still be there even after successful treatment, so more cancers might actually develop later.

Liver cancer: Prevention

For treating cancers, it not only depends on the type of treatment but also on financial strength. With the growing costs of the machines and drugs one should be able to overcome these. These kind of situations not effect at personal level of the patient.

Hepatoma can be a preventable disease. Hepatitis, alcohol abuse, and obesity can be avoided through

  • Social
  • Medical
  • Lifestyle changes

Also with this transition, there are some chances of improvement observed in the survival rates of liver cancer and hence there is a cause for optimisim.

Liver cancer: Prognosis

The outcome of hepatoma is extremely variable and depends as much upon the state of the liver and the person’s health as on any characteristic of the cancer itself. Therapies such as radiofrequency ablation, chemoembolization, cryoablation, radiosurgery, radioembolization, and systemic therapy are frequently performed sequentially over a patient’s lifetime, depending upon the changes as the disease progresses. Average survival for patients who are able to be treated with these methods is between one and two years.

Multiple techniques can be used in the extension of a patient’s life, while keeping them well and happy. Many drugs have been introduced for the treatment recognizing the molecular defects causing the cancer and few others are still under research. The evolution and improvement in radiologic and interventional technology has helped millions of people in prolongation of their lives. Also the survival rates was almost doubled since early 1990s. Increased and improved medical, scientific, and pharmaceutical areas helped to gain more attention for this disease and still make a better future.

Health tips:

  • Maintain a healthy weight
  • Regular exercise
  • Avoid fad diets (weight loss plans)
  • Limit in the intake of fat
  • Moderate alcohol consumption
  • Regular liver check-ups
  • Quit smoking
  • Be aware of drug risks
  • Vaccinations for hepatitis B

Turacoz Healthcare Solutions as a socially responsible company spreads the word and awareness and looks forward to collaboration or associations with other agencies/companies with similar goals and aspirations. We have a skilled and competent team of medical writers, clinicians, researchers and biostatisticians. Our clients include major pharmaceutical companies, hospitals and healthcare professionals. Our experience has been in supporting publications, creating regulatory documents, conducting observational studies, designing and creating for print and digital marketing as well as customizing sessions on medical writing. 

#LiverCancerAwarenessMonth

What is liver cancer or hepatic cancer?

Liver is the largest internal organ in the body. It is essential for the digestion of food. Cancers that start in the liver are known as primary liver cancers and if the cancer spreads from one part to the other part such as liver then it is called secondary liver cancers.

Epidemiology

According to the WHO, there are 745000 liver cancer deaths globally in 2012.

Liver cancer is the tenth most common cancer and the fifth most common cause of cancer death among men, and the ninth most common cause of cancer death among women.

The incidence of liver cancer varies widely throughout the world, with high rates in sub – Saharan Africa, eastern and southeastern Asia, and Melanesia and a low incidence in Northern and Western Europe and the Americas.

Causes

  • Infection with hepatitis viruses
  • Smoking
  • Low immunity
  • Systemic lupus erythematosus (SLE)
  • Family history
  • Diabetes
  • Radiation from X-rays and CT-scans
  • Body weight
  • Chemicals

Risk factors

  • Viral hepatitis
  • Cirrhosis
  • Obesity, Non-alcoholic fatty liver disease (NAFLD), and diabetes
  • Age
  • Gender
  • Environmental factors

Having more than one risk factor increases the risk of developing liver cancer more. For example, a person who carries both hepatitis B and C has a higher risk than a person carrying one type of the virus.

Signs and Symptoms

  • Pain, especially at the top right of the abdominal area, or near the right shoulder blade or in the back
  • Unexplained weight loss
  • A hard lump under the ribs on the right side of the body, which could be the tumor or a sign that the liver has increased in size
  • Weakness or fatigue

How is liver cancer diagnosed?

  • Physical examination
  • Blood tests
  • Ultrasound
  • Computed tomography (CT or CAT) scan
  • Magnetic resonance imaging (MRI)
  • Angiogram
  • Laparoscopy
  • Biopsy

Based on the test results, staging is done by doctors.

Types of liver cancer

There are a number of types of adult primary liver cancer. They are named for the type of cell from which the cancer develops.

Type of Liver Cancer Description How Common
Hepatocellular carcinoma (HCC) HCC can have different growth patterns. Some spread tentacle-like growths through the liver. Some start as a single tumor that spreads to other parts of the liver as the disease develops. Others develop as nodules at several different places in the liver. Occasionally, a pattern isn’t clear. Approximately 80% of adult primary liver cancers are hepatocellular carcinomas.
Cholangiocarcinoma, (or bile duct cancer) Develops from the cells in the bile duct of the liver. The bile duct is a thin tube that extends from the liver to the small intestine. The bile duct starts inside the liver as several smaller tubes that join together. About 10% to 20% of adult primary liver cancers are cholangiocarcinomas.
Angiosarcoma Starts in the blood vessels of the liver and grows very quickly. About 1% of adult primary liver cancers are angiosarcomas.

 

Turacoz Healthcare Solutions as a socially responsible company spreads the word and awareness and looks forward to collaboration or associations with other agencies/companies with similar goals and aspirations. We have a skilled and competent team of medical writers, clinicians, researchers and biostatisticians. Our clients include major pharmaceutical companies, hospitals and healthcare professionals. Our experience has been in supporting publications, creating regulatory documents, conducting observational studies, designing and creating for print and digital marketing as well as customizing sessions on medical writing.